Karakteristik Zat Metabolit Sekunder Dalam Ekstrak Bunga Krisan (Chrysanthemum Cinerariaefolium) Sebagai Bahan Pembuat Biopestisida

Abstract

The most common skin disorder worldwide is acne (acne vulgaris), acne is a chronic inflammatory disease that occurs in the pilosebaceous unit. The main factors involved in acne are increased sebum production, shedding of keratinocytes, bacterial growth and inflammation. Staphylococcus aureus bacteria play a role in the pathogenesis of acne by producing secondary metabolites which can react with sebum thereby increasing the inflammatory process. The content of antibacterial compounds in clove flowers are flavonoids, tannins, alkoloids, and euganol. The essential oil in clove flowers is also often used as an acne treatment because the gel preparation does not contain oil and has a hydrogel formulation so it does not make the skin too dry and will not exacerbate acne.